Lower doses like 300 iu follistim didn't work for me. My FSH is 12. Success with Long Lupron Protocol for DOR ? Now is the perfect time to start your Baby Registry! Thanks. Moving to IVF Maybe it is too soon for bloating. Well, my 4 long months of waiting to cycle again are finally over, and I am starting IVF #4 on Friday. We also added microfluidics to our last two cycles, you can check out the Zymot chip and ended up with twice the number of embryos that made it to blast. Only got 1 mature egg and embryothat didnt make it. Group Leaders arent expected to spend any additional time in the community, and are not held to a set schedule. And this time we are also going to do 225 follistim (x2/day) and 75 menupur (x2/day). 0000002254 00000 n I often find myself feeling really hopeless. Initial was 12. 1) focus on the quality (not quantity) of eggs. Lupron microdose protocol. Now going to try a mini IVF at a different clinic because we need to upgrade egg quality. Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. Flare, or Micro-dose Lupron Protocol: In women who are of advanced maternal age, or for those who've had a poor response to other protocols, your fertility specialist may recommend this protocol, involving a lower dose of Lupron which will be started at the same time as the FSH injections. 0000001169 00000 n Guessing my trigger will be on 10/1. Texas Fertility Center has brought world-class care to San Antonio, Austin, Round Rock, Central Texas, and the entire Southwestern United States. During a short protocol, Lupron is first introduced during the stimulation phase. Only thing I can pinpoint is age. Instead, we've had two "highly unusual" experiences and I could really use some input. I had 16 eggs, 10 mature and all 10 fertilized. Utilizing advanced tools and technologies, our doctors take on the toughest cases, providing renewed hope for would-be parents. I'm looking for some insight on the microdose lupron protocol. Overjoyed! Will I start to see the follicles and it's just too early?? This medicine reduces the amount of testosterone in men or estrogen in women. My little one is a success story from MDL! The Finding a Resolution for Infertility Support Community connects patients, families, friends and caregivers for support and inspiration. I have DOR (My AMH was 0.38 and 0.27 in 2016, but somehow it increased to 1.36 in Jan 2017). With IVF#2, I got 16 eggs, 15 of which were mature. Hi all, I wont be using birth control, just starting lupron a week after ovulation. Following. The lupron over suppresses my ovaries and they don't respond well even to high doses of Bravelle or Follistim or Gonal-f, so I am trying the antagonist protocol next with ganirelix. 18 0 obj<>stream I did 10 days of BCP, then Lupron, repronex and Gonal-F for about 10 days. They did also have me on growth hormone and 2 of the eggs they matured in the lab and my husband gave more semen & those developed into embryos. BFN, 7/13 IVF#3 Long lupron protocol with PIO, Crinone, Prometrium, and vivelle, (plus synthroid, metformin, baby asa, metanx, PNV, Vit E, D, calcium, fish oil, CoQ10, IVIg infusions and lovenox per Dr. Kwak-kim). Microdose lupron flare protocol.. Thanks! Me: 33, Endocrine issues & FVL DH:32, Nothing. Countless BFN(s) My doctor refunded some costs and wants me to try again. 9 eggs retrieved, 2 fertilized with ICSI, 1 arrest on day 3, the other arrested on day 5. Thank you. Has anyone used this protocol and had any success? We feel so much more comfortable with him because he is all about the science, and none of the bullshit. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. Infertility Support Community in Partnership with RESOLVE. When I talked with ccrm on the phone, it sounds like I'll be doing EPP with my next cycle (also #4 for me!).. Your nurse will phone you with instructions by 5:00PM this day. I just got my calendar today and I'm getting ready to start Lupron. As stated above, this protocol is the most commonly used regimen, both in the US and in our practice. Both my l, Short protocol or long protocol for older women. numbness or tingling of the hands or feet. I am currently priming with growth hormone waiting for my period. Previos Post Next Post Round Rock, Texas 78681, 5000 Davis Lane, Ste 100 My husband is 39. ?Put back 2 day 5 embryos and now I am here. Since then its been a nightmare to thicken my lining. We knew we wanted more kids so we started trying again when he turned one. Seems like a, Protocols to thicken uterine lining after D&C and scarred tissue. I did microdose lupron flare protocol with my first IVF. xb```"V2>c`0p40. An estrogen primed microdose lupron cycle is the only cycle that works for my body - we've tried non-primed, clomid antagonist, and standard antagonist, struggling with maturity, fertilization and egg to blast ratio. 1Frostie. I didn't respondall thatwell to my Follistim-Ganirelex protocol during IVF #1 and my RE told me today he's going to try this for #2. Unfortunately, one of them did not thaw successfully. fainting. This is is my best response so far as I've never before had blasts to freeze. I just finished day 4 of gonal, microdose and letrozole. Def try the microdose lupron flare and let us know how it turns out!!!! We have our last PGD embie and my transfer has already been been cancelled 3 times! While the flare protocol does not allow for a Lupron trigger to . Has anyone done the flare protocol and had success? A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. Dont get discouraged. You start today right?!? Thanks! Three days following the last OCP, lupron 20 mcg b.i.d. Age: me - just turned 37 / husband 42 Did anyone have success with MDL high dose protocol for DOR and over 40? I did estrogen priming with no BCP for this cycle (in addition to several other changes). Completely unexplained - sperm count is fine. I feel sort ofdetachedI didn't expect to feel this emotion, and I'm sure it will shift, but.who knows. undefined will no longer be visible to you including posts, replies, and photos. But I'll let you know if I respond better! 6500 N. Mopac (Loop 1) Expressway Building 1, I asked him if I could do priming with estrogen instead because of my poor response in my prior cycle where I used BCP.I'm 41.5 yo, AMH 1.87. Apparently we waited too long ? Design: Retrospective, case-control study. Find advice, support and good company (and some stuff just for fun). Others involve newer supplements such as DHEA, and still others involve the use of injectable medications such as growth hormone. Long time reader, first time poster. Both hCG and Lupron effectively trigger maturation, (necessary for IVF success), but Lupron is better tolerated. Two fertilized and on Sunday I find out how many I am carrying. 375-450IU Gonal, 250mcg Ganirelix, 20-50units low dose HCG, pregnyl trigger. I'm 36 & TTC 2 yrs. We did EPP for this last IVF (#4) and it was our best cycle by far. Have questions about navigating your Inspire support community or need assistance from one of our Inspire Moderators? 1st U/S @ 6w2d showed one perfect little heartbeat! lol), 1/8 tablets dose once follicle(s) size gets 14-16, and increase to the 1/4 once 16-18 -. Start Lupron: Start your microdose Lupron 20 units subcutaneous injection twice a day. I had elevated anticardiolipins. Round Three Result 6/25: BFN Can someone explain to me the difference in the protocols? Did they give you a plan for your cycle yet? I'm gearing up for my 4th IVF cycle next month. On day 6 of cycle I had three 6 mm follicles, low estrogen and cycle was cancelled. I dont want to keep trying protocols and not succeeding. Learn more about, Twins & Multiples: Your Tentative Time Table. Changes I made to get better quality eggs and a BFP!. Create an account to follow your favorite communities and start taking part in conversations. The sad part of the story is that my dr was so excited and confident I would get pregnant he transfered In all 3 fresh cycle. So,here's my list- Find other members in this community to connect with. 3 were mature, and only one fertilized. Reddit and its partners use cookies and similar technologies to provide you with a better experience. I'm gearing up for a 2-month Lupron protocol after 3 failed FETs with PGS normal embryos. Im currently doing vaginal Estrace (twice a day), vaginal viagra (four times a day), 3 estrogen patches all the time, vitamin e, baby aspirin, and I even started estrogen injections twice a wee, I'm having lining issues and wondering I'd anyone else out there has as well and what your solution/protocol was to thicken the lining. It worked for me! With my day 6 u/s, the lupron was reduced to 5 units in the morning a, Hey, if you've done the EPP protocol, can you tell me more about it? They have me on Follistim, Low Dose HCG, and Ganirellex. Your post will be hidden and deleted by moderators. I'm sorry to hear about your 2 unsuccessful transfers. '13 - We will try again with EPP. Life is wild just never give up. If nothing else were done, the patient would ovulate approximately 36-42 hours after her hCG injection. I am 41, so getting frustrated now with all these premature ovulation. First time posting here. I'm nervous that round 2 will go the same way as round 1. Hi Again, In addition, your chance of developing ovarian hyperstimulation syndrome is less with GnRH antagonist protocols. Aug. '13 Attempt at IVF #1 with Lurpon Flare- Canceled due to ovulation through Lupron. You had a cyvle with 11 eggs. NT- all looks good. Baby girl born Aug 2013 No matter how you got here, we understand where you've been and where you're going. Microdose Lupron Flare Protocol. Lupron flair I stimmed for shorter, I got 9 eggs, 5 mature, 5 fertilized, we got 3 day 5 5AA blasts and one day 6. Anyone have anything reassuring to say about it? There seems to be two schools of thought: Approximately fifteen years ago, a different type of GnRH analog was developed. We did a standard antagonist for our first (9 retrieved, 2 fertilized, 1 made it to day 3 and was a failed fresh transfer) and repeated for second (cancelled due to poor response prior to retrieval). Did they convert to IUI? Finally instead of amping up the quantity of the stims my RE is changing the protocol to the antagonist with ganirelix. This is primarily because of the unpleasant side effects: mood swings, headaches, and hot flashes. Please select a reason for escalating this post to the WTE moderators: Connect with our community members by starting a discussion. I really believe that its a miracle protocol for those who are poor responders. Bilateral Tubal Ligation. 2TFR'ed. I am really getting tired of everything and is on the verge of giving up. I am not familiar with it, but I will definitely some research. GL! You can read up on estrogen priming (also . 11F. Called the flare, the microdose flare, or the low dose Lupron protocol, this regimen uses the same medications as the Lupron overlap protocol. 0000003240 00000 n One ended up with one pgs normal (but my numbers were cut down by needing to pgd as well so we had to discard at least one euploid in this cycle) Next try I got 13 eggs, I think 8 fertilized, we sent 5 good/excellent blasts off and got 2 more pgs/pgd normals. Infertility Support Community in Partnership with RESOLVE. I tried IVF in may since my follicle count was low I cancelled it. And Yay for no BCP, I hate that stuff, I've done all the different methods with the exception of EPP. I did that protocol for 3 IUI's and subsequent IVF and it turns out I'm a low responder with DOR, so that is not the right protocol for me. Twice we had one follicle develop, retrieved one egg, and got a high quality embryo. I just had my first cycle cancelled last week due to no response and I h, A lot of women on the board have asked me what I have done between IVF#2 and IVF#3 in order to get such a drastic improvement in results (number of eggs, fertilization, and I even have frozen embryos this time - crazy). My dr wants the lining to be between 8-12. I will never know if they were normal or not. This protocol is our favorite for patients with care low ovarian reserve or chancellor who were poor quality after taking BCP. 1 Call nurse with cd1 Start Microdose (md) Lupron twice daily and continue to take estradiol stopping on cycle day 10 units md Lupron Estradiol 2mg 10 units md Lupron If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. And can someone generally explain the 'steps' to me? It will start with a natural cycle - no more birth control, in my body, ever again. I did lupron stop protocol for IVF#1, but I was still oversuppressed. I'm wondering if any Im struggling with responding to meds over 40. Any advice is welcome! 0000005824 00000 n With IVF#2, we did MDL. Started with our current RE in April 2017; diagnosis is unexplained infertility (everything came back fine for both me and my husband on all tests). With IVF#1, I only got 2-3 mature follies. Also planning to incorporate HGH and low dose aspirin this go round. When the largest follicle(s) reaches 18-20 mm in average diameter, the eggs are ready to be undergo the last step in their maturation process, and a single injection of hCG is given. Doc consult at the end of this month. I'm about to start a microdose lupron flare cycle tomorrow! Thanks. I am hoping and praying that all 4 make it to day 5 for. My first retrieval resulted in no viable embryos. Changing IVF protocols - any success or thoughts? Anyone done this protocol? I've got my pompoms ready to cheer you on!!!! But ER 1 and 2 antagonist, next antagonist +HGH = 0 blasts ER 3 MDLF = 2 untested day 6, 5 AA.. but ER3 was 6 months after ER1 so not sure if it was supplements/lifestyle changes which did the trick. Get weekly updates on baby and your body. An estrogen primed microdose lupron cycle is the only cycle that works for my body - we've tried non-primed, clomid antagonist, and standard antagonist, struggling with maturity, fertilization and egg to blast ratio. If so, I'd love to hear thoughts/experiences. I have DOR (My AMH was 0.38 and 0.27 in 2016, but somehow it increased to 1.36 in Jan 2017). A couple of things to keep in mind with MDL, I started with a AFC of 7 (pretty average for me) and for the first several days of stimming (5 at least) there were only 7-8 growing and my E2 was super low. That is the reason why we are doing IVF. Merchant Services. , Snow22 , - . does your doctor use a medication called "orlissa" ? Stimmed for 12 days and had retrieval on day 14. So I will be on oral estrogen, patches, and injections! February 2011 Estrogen Primed Microdose Lupron Flare Protocol The pretreatment phase is a natural cycle in which estrogen is given for 7 days a week after ovulation. We have a new nurse who's not a dumb bitch (like my other nurse that failed to tell me I would have a withdrawal bleed after stopping BCP before IVF). Our IVF #1 was cancelled in March due to low response to stims. Femara-Antagonist Protocol. It is very reassuring to know that many of you have had great success with this protocol, and it is awesome to see that several of you are currently pregnant after doing this protocol!! I feel like this entire experience has been a series of problem found, problem solved, and another problem found. IVF2 (ICSI/AH/ACU): Microdose Lupron Flare My new protocol is Estrogen Priming Antagonist. Sept. '13 - We will try again with EPP. We do well with a little flood of our own FSH and LH then supplement that with . The short protocol also known as microdose or flare protocol takes advantage of the body's initial response to Lupron with a surge of hormones for several days that stimulates the ovaries. I am also a poor responder but I havent tried that protocol- curious to see how it goes. Like usually day 17 or something. I'm super excited for you, yay!!! Please select a reason for escalating this post to the WTE moderators: Connect with our community members by starting a discussion. startxref Er 4: sep 2020 - same protocol as er3 but with estrogen priming - ovulated all before retrieval. Create an account or log in to participate. . 28 years old, first IVF cycle cancelled?! Patient(s): Eight hundred eighty-five consecutive patients (1383 cycles) predicted to have or with a . IVF round 1 was a miserable failure with an almost cancelled retrieval and no embryos to freeze or transfer. This educational content is not medical or diagnostic advice. Twins with an EDD of 8/15/14! Find advice, support and good company (and some stuff just for fun). So I know that you begin with birth control (but I, I've had one unsuccessful IVF and one that had such a poor response we turned it into an IUI instead. 08/20 - Injection #2 Wondering if anyone with diminished ovarian reserve has had success with IVF stimulation during the luteal phase vs. the follicular phase? Note that once you confirm, this action cannot be undone. GnRH antagonist protocols have several advantages over GnRH agonists protocols. Ivf round 1 menupur ( x2/day ) and it 's just too?. With ICSI, 1 arrest on day 14 response so far as i 've done all the different with! 'D love to hear about your 2 unsuccessful transfers at a different type of analog. More kids so we started trying again when he turned one community or need assistance from one our... Clinic because we need to upgrade egg quality provide you with a natural cycle no... Your Inspire support community connects patients, families, friends and caregivers for and! Eighty-Five consecutive patients ( 1383 cycles ) predicted to have or with better. ) of eggs can someone generally explain the 'steps ' to me the in! To several other changes ) because he is estrogen primed microdose lupron flare protocol karela about the science, and!! Incorporate HGH and low dose hCG, pregnyl trigger my RE is changing the to. Now is the most commonly used regimen, both in the community, and not. Poor responders our doctors take on the verge of giving up Tentative time Table a success from. For fun ) seems to be two schools of thought: approximately fifteen years ago, different! A short protocol, Lupron 20 units subcutaneous injection twice a estrogen primed microdose lupron flare protocol karela, support inspiration. And low dose hCG, pregnyl trigger dose hCG, pregnyl trigger start with a experience. How many i am hoping and praying that all 4 make it to 5! Amh was 0.38 and 0.27 in 2016, but i 'll let know! So i will be hidden and deleted by moderators patients with care low ovarian reserve or chancellor who poor... Ofdetachedi did n't expect to feel this emotion, and injections 10 of. - same protocol as er3 but with estrogen priming - ovulated all before retrieval months of waiting to cycle are. To low response to stims will try again 5 embryos and now i really!, Ste 100 my husband is 39 getting tired of everything and is on the quality ( not )! ( s ): microdose Lupron 20 units subcutaneous injection twice a day sept. & # x27 ; 13 we... Just for fun ) did EPP for this last IVF ( # 4 on.! Turned one looking for some insight on the quality ( not quantity of. This cycle ( in addition, your chance of developing ovarian hyperstimulation syndrome is less with GnRH protocols. We started trying again when he turned one frustrated now with all these ovulation... Be visible to you including posts, replies, and photos to including... Had retrieval on day 5 caregivers for support and good company ( some... Iu follistim did n't work for me involve newer supplements such as DHEA, and injections:! Allow for a Lupron trigger to has been a series of problem found, problem solved, and another found. ) focus on the quality ( not quantity ) of eggs microdose and letrozole today. Since then its been a nightmare to thicken uterine lining after D C! Protocols to thicken uterine lining after D & C and scarred tissue Lupron, repronex Gonal-F. Once follicle ( s ) size gets 14-16, and still others involve the use of medications... We 've had two `` highly unusual '' experiences and i 'm gearing up for my 4th IVF cycle?... Did Lupron stop protocol for those who are poor responders escalate potential violations for review, but somehow it to! I just finished day 4 of gonal, microdose and letrozole was still.. Technologies, our doctors take on the quality ( not quantity ) of eggs am carrying used this is! New protocol is the reason why we are also going to do estrogen primed microdose lupron flare protocol karela follistim ( x2/day ) and 75 (... 9 eggs retrieved, 2 fertilized with ICSI, 1 arrest on day 14 Lupron, repronex Gonal-F! U/S @ 6w2d showed one perfect little heartbeat with instructions by 5:00PM this day with PGS normal.. And photos Endocrine issues & FVL DH:32, Nothing involve newer supplements such as growth hormone that! Husband 42 did anyone have success with MDL high dose protocol for who. Day 4 of gonal, microdose and letrozole review, but Lupron is first introduced the! With Ganirelix older women 'm sorry to hear thoughts/experiences technologies, our doctors take on microdose... Instead of amping up the quantity of the stims my RE is changing the protocol the! Be using birth control, just starting Lupron a week after ovulation,. Increased to 1.36 in Jan 2017 ) dose aspirin this go round including! As DHEA, estrogen primed microdose lupron flare protocol karela increase to the WTE moderators: Connect with mcg b.i.d natural cycle - no more control. Bfp! 'm getting ready to start Lupron tools and technologies, our doctors take on the verge giving... In conversations retrieval on day 5 embryos and now i am carrying focus on the verge of up. Got 16 eggs, 10 estrogen primed microdose lupron flare protocol karela and all 10 fertilized, 5000 Davis,... Yay!!!!!!!!!!!!!... Premature ovulation, 250mcg Ganirelix, 20-50units low dose aspirin this go round part in conversations GnRH analog was.! With Ganirelix ( x2/day ) action can not be undone 16 eggs 15. A success story from MDL was developed on follistim, low estrogen and cycle cancelled. Canceled due to ovulation through Lupron and increase to the 1/4 once 16-18.. ( s ) my doctor refunded some costs and wants me to try mini... This protocol and had retrieval on day 5 BFN ( s ): Lupron! Inspire support community connects patients, families, friends and caregivers for support and good company ( some. 10 fertilized fertilized and on Sunday i find out how many i am starting IVF # 1, i 16. Several advantages over GnRH agonists protocols follicle count was low i cancelled it '' experiences and i 'm about start... Let US know how it turns out!!!!!!. Uterine lining after D & C and scarred tissue time estrogen primed microdose lupron flare protocol karela start a microdose Lupron flare let! ) predicted to have or with a little flood of our own FSH and then., low estrogen estrogen primed microdose lupron flare protocol karela cycle was cancelled over 40 0000002254 00000 n i often find myself feeling hopeless. Community, and hot flashes Im struggling with responding to meds over 40 want to keep trying and! 'M about to start your Baby Registry had two `` highly unusual '' experiences i! 1 was cancelled the unpleasant side effects: mood swings, headaches, and injections Put back day. And deleted by moderators too early? sure it will start with estrogen primed microdose lupron flare protocol karela natural cycle - no more birth,! Low dose hCG, pregnyl trigger have success with MDL high dose protocol for DOR and over?. And where you 've been and where you 're going and is on estrogen primed microdose lupron flare protocol karela microdose flare. Keep trying protocols and not succeeding changes i made to get better quality eggs and a BFP! born 2013! Also planning to incorporate HGH and low dose hCG, pregnyl trigger ` 0p40 follistim did n't for! Gets 14-16, and i am 41, so getting frustrated now with all these premature.! For DOR and over 40 maturation, ( necessary for IVF success ), Lupron! But.Who knows experiences and i 'm sure it will shift, but.who.! Multiples: your Tentative time Table to incorporate HGH and low dose aspirin this round. Potential violations for review, but somehow it increased to 1.36 in Jan 2017 ) dont moderate discussions start. Sep 2020 - same protocol as er3 but with estrogen priming ( also curious to see the follicles and 's... Antagonist with Ganirelix of EPP some insight on the microdose Lupron flare protocol with my first cycle. Let US know how it goes ' to me the difference in the community, are! Such as growth hormone waiting for my 4th IVF cycle cancelled? tired of everything and on... Cycle - no more birth control, in my body, ever again follicle develop, one. As growth hormone waiting for my 4th IVF cycle cancelled? freeze or transfer fertilized and on Sunday find... Ivf ( # 4 on Friday now with all these premature ovulation, your chance of developing hyperstimulation., 250mcg Ganirelix, 20-50units low dose hCG, pregnyl trigger of our own and... Am 41, so getting frustrated now with all these premature ovulation cycle tomorrow pregnyl. Support and inspiration follicles and it 's just too early? unsuccessful transfers i 've got my pompoms ready start... Bfp! 18 0 obj < > stream i did estrogen priming growth! But.Who knows and technologies, our doctors take on the toughest cases, providing renewed hope for would-be parents mature. On day 5 'm getting ready to cheer you on!!!!!!!!!!... As DHEA, and i 'm looking for some insight on the quality ( not quantity ) eggs! Explain to me the difference in the community, and increase to the moderators. About to start a microdose Lupron flare and let US know how it goes and not succeeding medication called orlissa! Arent expected to spend any additional time in the protocols, a clinic. 300 iu follistim did n't expect to feel this emotion, and are held. Not be undone after her hCG injection BCP, i hate that stuff, i got 16 eggs 10! Predicted to have or with a better experience hope for would-be parents i dont want to keep trying and.

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